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What are rs numbers (rsid)?

The raw data provided by 23andMe is an advanced view of all the uninterpreted raw genotype data, including data that is not used in 23andMe reports. This data has undergone a general quality review however only a subset of markers have been individually validated for accuracy. As such, the data from 23andMe's Browse Raw Data feature is suitable only for research, educational, and informational use and not for medical or other use.

The rs number is an accession number used by researchers and databases to refer to specific SNPs. It stands for Reference SNP cluster ID.

A SNP is a location in the genome that is known to vary between individuals. When researchers identify a SNP, they send a report (which includes the sequence immediately surrounding the SNP) to the dbSNP database. If overlapping reports are sent in, they are merged into the same, non-redundant Reference SNP cluster, which is assigned a unique rsid.

Genome-wide association studies linking SNPs to traits or conditions usually report their results by rsid. The rsid numbers for SNPs in Health and Traits reports can be found in the Scientific Details section.


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