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Does the 23andMe service include analysis of the MTHFR gene?

December 6 2013: Pending an FDA decision, 23andMe no longer offers new customers access to health reports. Customers who received their health information prior to November 22, 2013 will still be able to see their health reports, but those who purchased after that time will only receive their ancestry information as well as access to their uninterpreted raw data. These new customers may receive health reports in the future dependent on FDA marketing authorization.

23andMe does not sequence the entire MTHFR gene nor do we report on all MTHFR variants.

The current version of the 23andMe platform includes approximately 40 SNPs on the gene MTHFR, which is on chromosome 1. You can see the full list as well as your genotype at those positions within your account using the browse raw data feature. Currently one MTHFR variant, C677T (rs1801133), is incorporated into our Neural Tube Defects report. However, at this time other MTHFR SNPs are not incorporated into 23andMe's health reports. You can search your raw data by SNP using the unique RSID or browse SNPs by gene. You do need to know the unique RSID for your SNP of interest in order to search for it.

We cannot predict if any of these SNPs will be incorporated into future health reports, but will make additional information available to our customers as relevant peer-reviewed publications identify new associations.

You can find a complete list of the traits and conditions included in the 23andMe Personal Genome Service at

23andMe Services are for research, informational, and educational use only. We do not provide medical advice and the service has not been approved by the FDA for diagnostic testing. If you have concerns or questions about what you learn through 23andMe, you should contact your physician or other healthcare provider.

Note: 23andMe is not affiliated with any third-party interpretation services or healthcare providers, and cannot provide usage or analysis assistance related to such services or sites.

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